Josh Wolfe is the co-founder and managing partner at Lux Capital, which invests in the intersection of science and technology at the outermost edge of what is possible. He partners with innovators challenging the status quo and even the laws of nature. The more ambitious, the better.

Josh is a published scientist himself. He's a founding investor and board member with Bill Gates in Kymeta, a company that makes cutting-edge antennas for high-speed global satellite and space communications. And before Lux Capital, Josh worked in investment banking and capital markets. Afterwards, Josh co-founded Kurion, which used advanced robotics, engineering, and chemistry to clean up nuclear waste. In 2016, the company was bought for $400 million.

In this episode, we talk about it all: Biology, randomness, finance, consciousness, space, Brooklyn, investing, art, risk, and basketball. We start with what he learned growing up in Coney Island, a working class neighborhood in Brooklyn. Josh then shares his investment philosophy and why he likes investing in industries like lots of intellectual property, high barriers to entry and a limited talent pool. And finally, we talk about biology and the history of it— from single-celled organisms to the nature of consciousness — and Josh draws from his experience as a board member at the Santa Fe Institute. I hope you enjoy this wide-ranging conversation as much as I did.