Shuvomoy Das Gupta creates a summary blog post of Knuth's own writing as well as recorded interviews.

In Gupta's words:

In this blog, I am recording [Knuth's] thoughts on approaching a problem, organizing daily activities, and the pursuit of happiness.

There is lots of excellent content in here. However, one paragraph I particularly like is this one:

On the importance of anthropomorphizing a problem. "Another aspect of role playing is considerably more important: We can often make advances by anthropomorphizing a problem, by saying that certain of its aspects are "bad guys" and others are "good guys," or that parts of a system are "talking to each other." This approach is helpful because our language has lots of words for human relationships, so we can bring more machinery to bear on what we're thinking about."