Doctors are deemed a “triple threat” when they take care of patients, teach medical students, and conduct research. Mukherjee, who does all of these things at Columbia University, is a “quadruple threat,” because he’s also a Pulitzer Prize– winning author. In his latest book, Mukherjee guides us through the past, present, and future of genome science, with a special focus on huge ethical questions that the latest and greatest genome technologies provoke. Mukherjee wrote this book for a lay audience, because he knows that the new genome technologies are at the cusp of affecting us all in profound ways.